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K-Quinone-(Scientific Botanicals,
Inc) is an oil soluble source of vitamin K-1 (phytonadione), the
non-toxic natural form of vitamin K present in plants.
K-Quinone is extracted from alfalfa, nettles and green tea. It is now in a base of Olive Extract and Soy Extract.
Each drop provides 2 mg of vitamin K-1 activity.
The bottle is now 1/2 oz size and contains 440 doses put they have a shelf life of 6 months.
Because of this dating, returns will not be accepted on this product.
ACTIONS: Vitamin K-1 is necessary for changing glutamic acid to gamma
carboxy galutamic acid, which is specifically capable of binding
calcium ions. These changes take place in various sites such as:
(Kidney proteins-which inhibit formation of calcium oxalate stones,
Osteocalcin-which is needed for repair and remodeling of bones, and
Clotting factors II, VII, IX, and X. (1,2,3))
Vitamin K-1 administered several days before birth has beneficial
effects on the relative prothrombin deficiency commonly seen in
neonates. When given orally to nursing mothers vitamin K-1 is easily
passed through the breast milk to the infant and can reduce the risk of
hypoprothrombenemia in breast fed infants. (7)
*Proteins C and S which have fibrinolytic and anticoagulant activities are also vitamin K-1 dependent. (4)
*Vitamin K-1 has demonstrated anti-inflammatory activity by decreasing
the complement cascade, and also by potentiating the anti-inflammatory
effects of steroids. (5,6)
* Vitamin K-1 has demonstrated an analgesic effect nearly as effective
as that of morphine and barbiturates when injected in patients with
inoperable carcinomas. (8)
USES as VITAMIN k Supplement: K-Quinone provides a natural and non-toxic
source of vitamin K-1, as opposed to menadione, the water soluble form,
and may be prescribed for patients in whom a vitamin K-1 deficiency is
suspected. A wide range of medications have been shown to reduce
vitamin K-1 levels including anticonvulsants, analgesics, antibiotics,
and anticoagulants. Patients taking any of these medications may
develop disorders of clotting or calcium metabolism indicating the need
for supplemental K-Quinone. Calcium Dysmetabolism:
Additional vitamin K-1 is indicated for patients with kidney stones,
osteoporosis, fractures, or other disorders of calcium metabolism.
Clotting Disorders: Hypoprothrombenemia or the presence of these
bleeding disorders would be an indication for additional Vitamin K.
Vitamin K may be indicated in clotting disorders as well as bleeding
problems because several fibrinolytic proteins are vitamin K dependant.
Thus vitamin K may be thought of as having as alternative effect on the
clotting cascade.
Anti-Inflammatory: K-Quinone may be utilized in situations where one
wishes to potentiate the anti-inflammatory, antigranulomatous activity
of steroids. This could be combined with Lick-Rich and Ananacur to
further reduce the need for exogenous steroids while maintaining
similar therapeutic results without side effects.
Dosage: Up to ten drops twice daily with meals for adults.
References:
1. J. Biol. Chem 1981: 256;3936 Purification and isolation of a calcium
oxalate monohydrate crystal growth inhibitor from human kidney tissue
culture medium.
2. Nut. Rev. 1979:37;54 Osteocalcin: A Vitamin K dependent calcium binding protein in bone.
3. Lancet Aug. 4, 1984 p. 283 circulating Vitamin K-1 levels in fractured neck of femur.
4. N.E.J.M. 1984: 310; 1458 vitamin K dependent proteins.
5. Arch. Of Pharmacol. 1979: 307;185 Anti-inflammatory effect of warfarin and vitamin K-1.
6. Endocrinology 1965: 76;780 Antigranulomatous activity of vitamin K-1 and its summation with that of prednisolone.
7. Amer. J. Dis. Children 1942: 64;462 Percutaneous absorption of Vitamin K.
8. P.S.E.B.M. 1955: 90; 660 Analgesic property of Vitamin K-12 |
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